PROHIST

Table Description: Prodromal History

Detailed notes for this table are included below.

2.0 Data Dictionary

Table Constraints: PATNO, VISIT_ID

ITM_NAME

DSCR

ITM_TYPE

PROSCRN

Indicate how the participant was identified for Prodromal Screening

NUMBER

PRORBDENRL

Is the participant in the REM sleep behavior disorder (RBD) sub-group

BOOLEAN

RBDPATRPT

Participant reported RBD supports selection to RBD sub-group

BOOLEAN

RBDQUEST

RBD questionnaires supports selection to RBD sub-group

BOOLEAN

RBDDIAG

Does the participant have a clinical diagnosis of RBD

BOOLEAN

RBDDISYDT

Date of RBD symptom onset prior to RBD diagnosis

DATE

RBDDIDT

Date of clinical diagnosis of RBD

DATE

RBDPSG

Does the participant have a polysomnography (PSG) consistent with diagnosis of RBD

BOOLEAN

RBDPSSYDT

Date of RBD symptom onset prior to PSG consistent with diagnosis of RBD

DATE

RBDPSDT

Date of PSG

DATE

PROGENENRL

Is the participant in the genetic variant subgroup

BOOLEAN

GENENRLIU

Indicate how test results were confirmed

NUMBER

PROHYPENRL

Is the participant in the hyposmia (general risk) subgroup

BOOLEAN

PRO1FAMPD

Does the participant have a biological first degree family member with PD

BOOLEAN

PROSYNBYP

Does the participant have a known synuclein positive biopsy

BOOLEAN

PROPREVHYP

Does the participant have previously known hyposmia (testing completed prior to PPMI participation)

BOOLEAN

2.0 Code Book

ITM_NAME

CODE

DECODE_2.0

GENENRLIU

1

Genetic testing completed through the IU Screening Core

GENENRLIU

2

Previous genetic test report reviewed and approved by the IU Screening Core

PRO1FAMPD

0

No

PRO1FAMPD

1

Yes

PROGENENRL

0

No

PROGENENRL

1

Yes

PROHYPENRL

0

No

PROHYPENRL

1

Yes

PROPREVHYP

0

No

PROPREVHYP

1

Yes

PRORBDENRL

0

No

PRORBDENRL

1

Yes

PROSCRN

1

Participant was referred by the IU Screening Core

PROSCRN

2

Participant was identified by the PPMI clinical site

PROSYNBYP

0

No

PROSYNBYP

1

Yes

RBDDIAG

0

No

RBDDIAG

1

Yes

RBDPATRPT

0

No

RBDPATRPT

1

Yes

RBDPSG

0

No

RBDPSG

1

Yes

RBDQUEST

0

No

RBDQUEST

1

Yes

Details

As of February 2021, the PROHIST CRF (Prodromal History) was added to the PPMI 2.0 study as part of Amendment 2. This form is required at the Screening visit for all participants in the Prodromal Cohort.