CONMED¶
Table Description: Concomitant Medication Log
Detailed notes for this table are included below.
1.0 Description: Concomitant Medications
View Source CRFs¶
1.0 CRFs: Click on any PAG_NAME link below to be taken to the CRF used in the PPMI 1.0 Study.
2.0 CRFs: Click on any PAG_NAME link below to be taken to a screenshot of how this eCRF is currently implemented in the PPMI 2.0 Study.
2.0 Data Dictionary¶
Table Constraints: PATNO, SEQNO
ITM_NAME |
DSCR |
ITM_TYPE |
ITM_TYPE_1.0 |
|---|---|---|---|
SEQNO |
Sequence Number |
NUMBER |
|
CMTRT |
Medication |
TEXT |
CHAR |
CMINDC |
Indication |
NUMBER |
CHAR |
CMINDCCM |
Other indication comment |
TEXT |
|
STARTDT |
Start Date |
DATE |
DATE |
STOPDT |
Stop Date |
DATE |
DATE |
2.0 Code Book¶
ITM_NAME |
CODE |
DECODE_2.0 |
DECODE_1.0 |
|---|---|---|---|
CMINDC |
1 |
Anxiety |
|
CMINDC |
2 |
Atrial Fibrillation / Arrhythmias |
|
CMINDC |
3 |
Benign Prostatic Hypertrophy / Overactive Bladder |
|
CMINDC |
4 |
Cognitive Dysfunction |
|
CMINDC |
5 |
Congestive Heart Failure |
|
CMINDC |
6 |
Constipation |
|
CMINDC |
7 |
Coronary Artery Disease, Peripheral Artery Disease, Stroke |
|
CMINDC |
8 |
Daytime Sleepiness |
|
CMINDC |
9 |
Delusions, Hallucination, Psychosis |
|
CMINDC |
10 |
Depression |
|
CMINDC |
11 |
Diabetes |
|
CMINDC |
12 |
GERD |
|
CMINDC |
13 |
Hyperlipidemia |
|
CMINDC |
14 |
Hypertension |
|
CMINDC |
15 |
Insomnia |
|
CMINDC |
16 |
Nausea |
|
CMINDC |
17 |
Pain |
|
CMINDC |
18 |
REM-Behavior Disorder |
|
CMINDC |
19 |
Restless Leg Syndrome |
|
CMINDC |
20 |
Sexual Dysfunction |
|
CMINDC |
21 |
Sialorrhea / Drooling |
|
CMINDC |
22 |
Supplements / Homeopathic Medication |
|
CMINDC |
23 |
Thyroid Disorder |
|
CMINDC |
24 |
Vitamins / Coenzymes |
|
CMINDC |
25 |
Other |
Missing Columns¶
ITM_NAME |
DSCR_1.0 |
|---|---|
CMDOSE |
Dose |
CMDOSFRQ |
Frequency |
CMDOSU |
Units |
CMSEQ |
Row # |
DISMED |
PD Med ? |
EXCLMED |
Exclusionary Med flag |
INVSTAFF |
Investigator staff code |
LEDD |
LEDD calculation for PD medication |
ONGOING |
Ongoing |
PD_MOTOR_MED |
Medication affects PD Motor assessments 0=No; 1=Yes |
RECNO |
WHO RECNO |
ROUTE |
Route |
SEQNO1 |
WHO SEQNO1 |
SEQNO2 |
WHO SEQNO2 |
STARTEST |
Start Date estimation |
STOPEST |
Stop Date estimation |
TOTDDOSE |
Total Daily Dose |
WHODRUG |
WHO DRUG NAME |
Details¶
CMINDC
In PPMI 1.0 this variable was a free text field. In PPMI 2.0 indications are chosen from a pre-determined list. This was done in the interest of simplifying this log and avoiding typing and spelling errors.
SEQNO
This variable was added to replace the 1.0 variable CMSEQ. This was done to standardize the sequence number variables in all log forms which in PPMI 1.0 had included a mix of variables named SEQNO and ones named per-table. Sequence numbers in PPMI 2.0 are not manually recorded in the log but are instead derived in post-processing. This transformation is standard for all log forms.
Date Estimation
STARTEST and STOPEST have been removed from this table following a study-wide decision to remove indications of date estimation from all CRFs.
LEDDLOG
The variables LEDD, PD_MOTOR_MED and DISMED were removed because all Levodopa-Equivalent medications are now being captured in the LEDDLOG table.
Deprecated Variables
The CONMED log has been simplified signifigantly and no longer includes the details captured by CMDOSE, CMDOSU, CMDOSFRQ, ROUTE, TOTDDOSE, and ONGOING.
Derived Variables
EXCLMED: This variable will be derived following the creation of a list of exclusionary medications thatCMTRTcan be compared to.WHODrug: The four variables
SEQNO1,SEQNO2,WHODRUG, andRECNOassociated with the WHODrug coding system will be derived fromCMTRTin a to-be-determined manner.