NUPDRS2P¶

Table Description: MDS-UPDRS Part II Patient Questionnaire: Motor Aspects of Experiences of Daily Living (M-EDL)

Detailed notes for this table are included below.

1.0 Description: nUPDRS Part II: Patient Questionnaire

View Source CRFs¶

2.0 CRFs: Click on any PAG_NAME link below to be taken to a screenshot of how this eCRF is currently implemented in the PPMI 2.0 Study.

NUPDRSP

2.0 Data Dictionary¶

Table Constraints: PATNO, VISIT_ID

ITM_NAME	DSCR	ITM_TYPE	ITM_TYPE_1.0
NUPSOURC	Primary Source of Information	NUMBER	CHAR
NP2SPCH	SPEECH	NUMBER	NUMBER
NP2SALV	SALIVA + DROOLING	NUMBER	NUMBER
NP2SWAL	CHEWING AND SWALLOWING	NUMBER	NUMBER
NP2EAT	EATING TASKS	NUMBER	NUMBER
NP2DRES	DRESSING	NUMBER	NUMBER
NP2HYGN	HYGIENE	NUMBER	NUMBER
NP2HWRT	HANDWRITING	NUMBER	NUMBER
NP2HOBB	DOING HOBBIES AND OTHER ACTIVITIES	NUMBER	NUMBER
NP2TURN	TURNING IN BED	NUMBER	NUMBER
NP2TRMR	TREMOR	NUMBER	NUMBER
NP2RISE	GETTING OUT OF BED, CAR, OR DEEP CHAIR	NUMBER	NUMBER
NP2WALK	WALKING AND BALANCE	NUMBER	NUMBER
NP2FREZ	FREEZING	NUMBER	NUMBER

2.0 Code Book¶

ITM_NAME	CODE	DECODE_2.0	DECODE_1.0
NP2DRES	0	Normal: Not at all (no problems).
NP2DRES	1	Slight: I am slow, but I do not need help.
NP2DRES	2	Mild: I am slow and need help for a few dressing tasks (buttons, bracelets).
NP2DRES	3	Moderate: I need help for many dressing tasks.
NP2DRES	4	Severe: I need help for most or all dressing tasks.
NP2EAT	0	Normal: Not at all (no problems).
NP2EAT	1	Slight: I am slow, but I do not need any help handling my food and have not had food spills while eating.
NP2EAT	2	Mild: I am slow with my eating and have occasional food spills. I may need help with a few tasks such as cutting meat.
NP2EAT	3	Moderate: I need help with many eating tasks but can manage some alone.
NP2EAT	4	Severe: I need help for most or all eating tasks.
NP2FREZ	0	Normal: Not at all (no problems).
NP2FREZ	1	Slight: I briefly freeze but I can easily start walking again. I do not need help from someone else or a walking aid (cane or walker) because of freezing.
NP2FREZ	2	Mild: I freeze and have trouble starting to walk again, but I do not need someone’s help or a walking aid (cane or walker) because of freezing.
NP2FREZ	3	Moderate: When I freeze I have a lot of trouble starting to walk again and, because of freezing, I sometimes need to use a walking aid or need someone else’s help.
NP2FREZ	4	Severe: Because of freezing, most or all of the time, I need to use a walking aid or someone’s help.
NP2HOBB	0	Normal: Not at all (no problems).
NP2HOBB	1	Slight: I am a bit slow but do these activities easily.
NP2HOBB	2	Mild: I have some difficulty doing these activities.
NP2HOBB	3	Moderate: I have major problems doing these activities, but still do most.
NP2HOBB	4	Severe: I am unable to do most or all of these activities.
NP2HWRT	0	Normal: Not at all (no problems).
NP2HWRT	1	Slight: My writing is slow, clumsy or uneven, but all words are clear.
NP2HWRT	2	Mild: Some words are unclear and difficult to read.
NP2HWRT	3	Moderate: Many words are unclear and difficult to read.
NP2HWRT	4	Severe: Most or all words cannot be read.
NP2HYGN	0	Normal: Not at all (no problems).
NP2HYGN	1	Slight: I am slow, but I do not need help.
NP2HYGN	2	Mild: I need someone else to help me with some hygiene tasks.
NP2HYGN	3	Moderate: I need help for many hygiene tasks.
NP2HYGN	4	Severe: I need help for most or all of my hygiene tasks.
NP2RISE	0	Normal: Not at all (no problems).
NP2RISE	1	Slight: I am slow or awkward, but I usually can do it on my first try.
NP2RISE	2	Mild: I need more than one try to get up or need occasional help.
NP2RISE	3	Moderate: I sometimes need help to get up, but most times I can still do it on my own.
NP2RISE	4	Severe: I need help most or all of the time.
NP2SALV	0	Normal: Not at all (no problems).
NP2SALV	1	Slight: I have too much saliva, but do not drool.
NP2SALV	2	Mild: I have some drooling during sleep, but none when I am awake.
NP2SALV	3	Moderate: I have some drooling when I am awake, but I usually do not need tissues or a handkerchief.
NP2SALV	4	Severe: I have so much drooling that I regularly need to use tissues or a handkerchief to protect my clothes.
NP2SPCH	0	Normal: Not at all (no problems).
NP2SPCH	1	Slight: My speech is soft, slurred or uneven, but it does not cause others to ask me to repeat myself.
NP2SPCH	2	Mild: My speech causes people to ask me to occasionally repeat myself, but not everyday.
NP2SPCH	3	Moderate: My speech is unclear enough that others ask me to repeat myself every day even though most of my speech is understood.
NP2SPCH	4	Severe: Most or all of my speech cannot be understood.
NP2SWAL	0	Normal: No problems.
NP2SWAL	1	Slight: I am aware of slowness in my chewing or increased effort at swallowing, but I do not choke or need to have my food specially prepared.
NP2SWAL	2	Mild: I need to have my pills cut or my food specially prepared because of chewing or swallowing problems, but I have not choked over the past week.
NP2SWAL	3	Moderate: I choked at least one in the past week.
NP2SWAL	4	Severe: Because of chewing and swallowing problems, I need a feed tube.
NP2TRMR	0	Normal: Not at all. I have no shaking or tremor.
NP2TRMR	1	Slight: Shaking or tremor occurs but does not cause problems with any activities.
NP2TRMR	2	Mild: Shaking or tremor causes problems with only a few activities.
NP2TRMR	3	Moderate: Shaking or tremor causes problems with many of my daily activities.
NP2TRMR	4	Severe: Shaking or tremor causes problems with most or all activities.
NP2TURN	0	Normal: Not at all (no problems).
NP2TURN	1	Slight: I have a bit of trouble turning, but I do not need any help.
NP2TURN	2	Mild: I have a lot of trouble turning and need occasional help from someone else.
NP2TURN	3	Moderate: To turn over I often need help from someone else.
NP2TURN	4	Severe: I am unable to turn over without help from someone else.
NP2WALK	0	Normal: Not at all (no problems).
NP2WALK	1	Slight: I am slightly slow or may drag a leg. I never use a walking aid.
NP2WALK	2	Mild: occasionally use a walking aid, but I do not need any help from another person.
NP2WALK	3	Moderate: I usually use a walking aid (cane, walker) to walk safely without falling. However, I do not usually need the support of another person.
NP2WALK	4	Severe: I usually use the support of another persons to walk safely without falling.
NUPSOURC	1	Patient	Patient
NUPSOURC	2	Caregiver	Caregiver
NUPSOURC	3	Patient and Caregiver in Equal Proportion	Patient and Caregiver - Equal Proportion

Details¶

In the EDC, the MDS-UPDRS Part I and Part II patient questionnaires were combined into one form (NUPDRSP). They were split back out into their respective tables (NUPDRS1P and NUPDRS2P) during the transfer to LONI, which matches the 1.0 structure. The NUPDRS2P table is conceptually the same between 1.0 and 2.0. Two small design differences have been outlined below.

PAG_NAME

In 1.0, the PAG_NAME for this table was NUPDRS2P while in 2.0 the PAG_NAME is NUPDRSP. This is due to the design of the EDC. PAG_NAME is not seen in the above representation of the data dictionary, because it is a standard variable present in all tables derived from CRFs. However, you can see the PAG_NAME in the downloadable version of the PPMI 2.0 data dictionary.

Codebook

Besides NUPRSOURC, no variables from the NUPDRS2P table were included in PPMI 1.0’s Code List. In 2.0, all variable options from the NUPDRS2P table have been added to the codebook to document what the different codes mean for each question.